Integrated Aesthetics

Upneeq

Upneeq® is the only FDA-approved prescription eyedrop for low-lying eyelids and helps to lift the upper eyelids and open your eyes to a more youthful, refreshed appearance for up to 6 hours.

Avg Cost: $220
Avg Recovery: No Downtime
Discomfort Level:
Anesthesia: None

Upneeq® is the only FDA-approved prescription eye drop for low-lying eyelids and helps to lift the upper eyelids and open your eyes to a more youthful, refreshed appearance for up to 6 hours. One drop of Upneeq should be inserted once a day, one drop per eye. Upneeq contains oxymetazoline, an alpha adrenergic agonist that triggers the levator palpebra muscle, causing the muscle to contract and raise the upper eyelid.

Most patients in clinical trials had a lift in their eyelids in as little as 2 hours, 84% of patients had some level of improvement, and 74% of patients had more than a 50% improvement. In one study, some patients saw a lift in their eyelids as fast as 5 minutes after the first dose.  

In clinical trials, Upneeq helped patients with acquired ptosis see more—on the first day of treatment! 87.8% of patients had some level of improvement and 40.8% of patients had at least a 50% improvement on Day 14 (2 hours after applying Upneeq) 

If you are bothered by your eyelids, Dr. Cho and Dr. Chiang can help evaluate if you are a candidate for Upneeq. Upneeq helps those with acquired ptosis (low-lying lids) which is a common condition that affects adults of all ages but occurs more often with increased age. Acquired ptosis usually occurs when the muscles in the eyelid stretch and weaken, causing the lid to droop. Acquired ptosis can also be caused by other issues, such as cataract surgery, contact lenses, or an underlying medical condition. 

Acquired ptosis can also impact your eyesight by reducing your field of vision and day to day eye functions such as riding, driving and computer use. It can also make you look tired, appear to have asymmetrical eyes and give you cosmetic concerns. 

What is Upneeq? 

Upneeq® (oxymetazoline hydrochloride ophthalmic solution), 0.1% is a prescription eyedrop used to treat low-lying lids in adults. 

How long does Upneeq last?

One drop of Upneeq was shown to last for at least 6 hours in clinical studies. One prescription contains enough drops for 45 days.

How do I apply Upneeq? 

Apply Upneeq to your eye(s) in 2 easy steps  

  1. Cut open foil wrapper and remove single-use vial 
  2. Apply one drop of Upneeq in each affected eye as directed, once a day. Do not let the tip of the vial touch your eye or any other surface. Vials should not be re-used after opening and should be thrown away after applying drop(s). If you wear contact lenses, remove them before applying Upneeq eyedrops. You may put them back in 15 minutes after applying Upneeq. If more than one topical ophthalmic drug is being used, the drugs should be administered at least 15 minutes between applications

What are the most common side effects of Upneeq?  

The most common adverse reactions with Upneeq (occurring in 1-5% of patients) were eye inflammation, eye redness, dry eye, blurred vision, eye pain at time of use, eye irritation, and headache. 

What warnings and precautions are associated with Upneeq? 

Low-lying lids may be related to conditions such as stroke and/or brain aneurysm, Horner syndrome, myasthenia gravis, loss of the ability to move eye muscles, eye infection and eye tumors. Ask your doctor if you have any of these conditions. 

What are the most common side effects of Upneeq (oxymetazoline hydrochloride ophthalmic solution), 0.1%? 

The most common adverse reactions with Upneeq (occurring in 1-5% of patients) were eye inflammation, eye redness, dry eye, blurred vision, eye pain at time of use, eye irritation, and headache. 

What should my doctor know about before prescribing me Upneeq?  

  • Your doctor should review your full medical history before prescribing Upneeq. 
  • Upneeq belongs to a class of medication (alpha-adrenergic agonists) that may affect your blood pressure. Use Upneeq carefully if you currently take an alpha-adrenergic antagonist medication to treat heart disease or an enlarged prostate. Patients taking beta-blockers, or other medications to treat hypertension or an abnormal heartbeat, should also be careful when using Upneeq. 
  • Patients who use a certain class of antidepressant medication (monoamine oxidase inhibitors) should also be careful when using Upneeq, as it may affect the way your body absorbs the medication.

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We are an integrated cosmetic plastic surgery, dermatology and medspa practice dedicated to helping you live your best life through the lens of aesthetics.
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